Kam Ming Ko Selected Research

Hypoxia (Hypoxemia)

7/2014	β-Sitosterol enhances cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration: protection against oxidant injury in H9c2 cells and rat hearts.
1/2013	Ursolic-Acid-Enriched Herba Cynomorii Extract Protects against Oxidant Injury in H9c2 Cells and Rat Myocardium by Increasing Mitochondrial ATP Generation Capacity and Enhancing Cellular Glutathione Redox Cycling, Possibly through Mitochondrial Uncoupling.
1/2013	Herba Cistanches stimulates cellular glutathione redox cycling by reactive oxygen species generated from mitochondrial respiration in H9c2 cardiomyocytes.
3/2012	Cytochrome P-450-catalyzed reactive oxygen species production mediates the (-)schisandrin B-induced glutathione and heat shock responses in H9c2 cardiomyocytes.
1/2012	Danshen-Gegen decoction protects against hypoxia/reoxygenation-induced apoptosis by inhibiting mitochondrial permeability transition via the redox-sensitive ERK/Nrf2 and PKCε/mKATP pathways in H9c2 cardiomyocytes.
4/2011	Schisandrin B elicits a glutathione antioxidant response and protects against apoptosis via the redox-sensitive ERK/Nrf2 pathway in H9c2 cells.
11/2009	Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and associated changes in the Ca(2+)-induced mitochondrial permeability transition and mitochondrial membrane potential in AML12 hepatocytes.
5/2008	Schisandrin B stereoisomers protect against hypoxia/reoxygenation-induced apoptosis and inhibit associated changes in Ca2+-induced mitochondrial permeability transition and mitochondrial membrane potential in H9c2 cardiomyocytes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Kam Ming Ko Research Topics

Disease

9	Reperfusion Injury 08/2011 - 01/2003
8	Hypoxia (Hypoxemia) 07/2014 - 05/2008
7	Ischemia 01/2013 - 01/2003
5	Myocardial Ischemia (Ischemic Heart Diseases) 05/2010 - 11/2004
4	Inflammation (Inflammations) 09/2020 - 01/2015
3	Coronary Disease (Coronary Heart Disease) 08/2011 - 02/2011
2	Weight Loss (Weight Reduction) 07/2020 - 01/2015
2	Retinal Degeneration 01/2016 - 01/2016
2	Brain Ischemia (Cerebral Ischemia) 07/2012 - 07/2008
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2012 - 01/2012
2	Atherosclerosis 08/2011 - 04/2011
1	Rhinitis 09/2020
1	Asthma (Bronchial Asthma) 09/2020
1	Allergic Rhinitis 09/2020
1	Body Weight (Weight, Body) 07/2020
1	Obesity 07/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2020
1	Tourette Syndrome (Tourette's Syndrome) 01/2019
1	Non-alcoholic Fatty Liver Disease 01/2016
1	Edema (Dropsy) 01/2016
1	Peritonitis 09/2015
1	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2015
1	Yang Deficiency (Xu, Yang) 01/2015
1	Carcinoma (Carcinomatosis) 07/2013
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/2013
1	Stroke (Strokes) 07/2012
1	Neuroblastoma 07/2012
1	Huntington Disease (Huntington's Disease) 05/2012
1	Necrosis 05/2012
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2012
1	Dementia (Dementias) 08/2011
1	Memory Disorders (Memory Loss) 08/2011
1	Myocardial Infarction 02/2011
1	Pheochromocytoma 01/2011
1	Parkinson Disease (Parkinson's Disease) 01/2011
1	Neoplasms (Cancer) 09/2009
1	Hepatitis 11/2004

Drug/Important Bio-Agent (IBA)

13	schizandrin BIBA 01/2016 - 01/2003
9	AntioxidantsIBA 01/2019 - 10/2005
8	Glutathione (Reduced Glutathione)IBA 07/2014 - 01/2003
7	Adenosine Triphosphate (ATP)IBA 09/2015 - 01/2003
4	Caspase 3 (Caspase-3)IBA 07/2013 - 05/2008
4	Danshen-GegenIBA 01/2012 - 02/2011
3	Pharmaceutical PreparationsIBA 03/2012 - 05/2008
2	Protein Kinases (Protein Kinase)IBA 01/2015 - 09/2009
2	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2012 - 02/2006
2	schizandrinIBA 11/2009 - 05/2008
2	Cytochromes c (Cytochrome c)IBA 11/2009 - 05/2008
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 11/2009 - 05/2008
2	Emodin (Archin)IBA 08/2006 - 10/2005
2	Oleanolic AcidIBA 08/2006 - 02/2006
1	Immunoglobulin E (IgE)IBA 09/2020
1	Anti-Asthmatic Agents (Antiasthmatic Drugs)IBA 09/2020
1	Anti-Allergic Agents (Antiallergic Agents)IBA 09/2020
1	OvalbuminIBA 09/2020
1	Uncoupling Protein 3IBA 07/2020
1	TriterpenesIBA 07/2020
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019
1	CarrageenanIBA 01/2016
1	Nonesterified Fatty Acids (NEFA)IBA 01/2016
1	aluminum sulfate (alum)IBA 09/2015
1	gamma-sitosterol (beta-sitosterol)IBA 01/2015
1	Adenosine Monophosphate (AMP)IBA 01/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2015
1	EnzymesIBA 01/2015
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2015
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 07/2013
1	Ursolic AcidIBA 01/2013
1	Amyloid (Amyloid Fibrils)IBA 07/2012
1	Proteins (Proteins, Gene)FDA Link 07/2012
1	DNA (Deoxyribonucleic Acid)IBA 07/2012
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 05/2012
1	Oxidoreductases (Dehydrogenase)IBA 05/2012
1	Caspase 9IBA 05/2012
1	Pyruvic Acid (Pyruvate)IBA 05/2012
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2012
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 03/2012
1	Methanol (Carbinol)IBA 01/2012
1	Scopolamine (Hyoscine)FDA Link 08/2011
1	Acetylcholine (Acetylcholine Chloride)FDA Link 08/2011
1	LignansIBA 08/2011
1	Protein Kinase CIBA 04/2011
1	U 0126 (UO 126)IBA 04/2011
1	HerbicidesIBA 01/2011
1	ParaquatIBA 01/2011
1	Gentamicins (Gentamicin)FDA LinkGeneric 02/2008
1	Buthionine SulfoximineIBA 02/2006
1	alpha-Tocopherol FDA Link 02/2006
1	phoroneIBA 02/2006
1	Thioctic Acid (Lipoic Acid)IBA 02/2006
1	DDBIBA 08/2005
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 11/2004

Therapy/Procedure

1	Phytotherapy (Herbal Therapy) 01/2015
1	Therapeutics 09/2009
1	Radiotherapy 09/2009